Folic acid (as 5-MTHF by Quatrefolic) is required for proper neural tube closure between the 22nd and 28^th pregnancy when the woman might not even know that she is pregnant. This is why it is advised to women wanting children to daily consume folic acid at least four weeks before planned conception.
Because 5-MTHF does not require activation, it is immediately available to mother and fetus and does not accumulate in blood like folic acid does in cases of reduced hepatic transformation.

Omega-3 fatty acids, particularly DHA, are essential for fetal eyes and brain development.

Vitamin C supports the immune system and decreases the risk of iron deficiency anemia by favoring iron absorption. Vitamin E is an antioxidant of the cell membranes that slows-down cellular aging. Together with Vitamin C, Copper contributes to collagen synthesis and the maintenance of connective tissues. Vitamin D3 helps calcium fixation in the bones.

Vitamin B1, Niacin (Vitamin B3), Vitamin B6, and Pantothenic (Vitamin B5) acid play an essential role in nutrient assimilation and energy release from sugars and lipids. Vitamin B2 is required for cell protection, in particular nerve cells. Vitamin B12 is involved in cell growth and function and the balance of the nervous system. Biotin is used to build healthy skin, hair, and nails.

Iodine is essential for thyroid hormone production, which controls growth, energy-yielding metabolism, and fetus brain and bone development.

Iron is required for hemoglobin formation and oxygen transport. Zinc has an essential function in cell regeneration and protection. Together with Vitamin C, it strengthens the immune system.

Magnesium activates several enzymes and influences the energy-yielding metabolism and function of the neuromuscular system.